Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture

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Correction: Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture

0350 February 2005 | Volume 3 | Issue 2 | e80 | e90 Correction: Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture Damien Devos, Svetlana Dokudovskaya, Frank Alber, Rosemary Williams, Brian T. Chait, Andrej Sali, Michael P. Rout DOI: 10.1371/journal.pbio.0020380 In PLoS Biology, volume 2, issue 12. In Materials and Methods, the sentence “The magnetic ...

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Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture

Numerous features distinguish prokaryotes from eukaryotes, chief among which are the distinctive internal membrane systems of eukaryotic cells. These membrane systems form elaborate compartments and vesicular trafficking pathways, and sequester the chromatin within the nuclear envelope. The nuclear pore complex is the portal that specifically mediates macromolecular trafficking across the nucle...

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0350 February 2005 | Volume 3 | Issue 2 | e80 | e90 Correction: Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture Damien Devos, Svetlana Dokudovskaya, Frank Alber, Rosemary Williams, Brian T. Chait, Andrej Sali, Michael P. Rout DOI: 10.1371/journal.pbio.0020380 In PLoS Biology, volume 2, issue 12. In Materials and Methods, the sentence “The magnetic ...

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Nuclear pore complexes

What do they look like? A picture is worth twice the length of this article (Figure 1). All eukaryotes have these impressive structures: vertebrates have the Cadillac model (~125 MDa) and yeast a sportier version (~50 MDa). In spite of their immense size, these structures are made of a relatively small number of proteins — about 30 — the so-called nucleoporins or nups. Defining an NPC ‘interact...

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The nuclear pore complex: from molecular architecture to functional dynamics.

Toward dissecting the molecular composition and architecture of the nuclear pore complex (NPC), over the past 18 months novel nucleoporins and NPC subcomplexes were identified and characterized. The three-dimensional structure of isolated yeast NPCs was determined by electron cryomicroscopy. New specimen preparation and labeling protocols localized a number of nucleoporins and NPC subcomplexes ...

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ژورنال

عنوان ژورنال: PLoS Biology

سال: 2004

ISSN: 1545-7885

DOI: 10.1371/journal.pbio.0020380